\n
<\/p>\n
Inflamacioni ose reaksioni inflamator \u00ebsht\u00eb nj\u00eb aft\u00ebsi stereotipike, komplekse, e fituar nga zhvillimi i organizmave t\u00eb gjall\u00eb p\u00ebr t’iu p\u00ebrgjigjur d\u00ebmtimeve t\u00eb ndryshme, simptomat e t\u00eb cilave jan\u00eb: eritema (skuqje), gung\u00eb (\u00ebnjtje), inflamacion (nxeht\u00ebsi), ndjeshm\u00ebri (dhimbje) dhe functio laesa. (funksioni i d\u00ebmtuar) . N\u00eb rastin e s\u00ebmundjeve metabolike kronike, si diabeti i tipit 2 ose obeziteti, n\u00eb nivel qelizor p\u00ebrdoren mekanizma dhe molekula t\u00eb ngjashme sinjalizuese si n\u00eb inflamacionet klasike, por simptomat e m\u00ebsip\u00ebrme nuk shfaqen. P\u00ebr k\u00ebto kushte kronike \u00ebsht\u00eb propozuar em\u00ebrtimi “inflamacion i shkall\u00ebs s\u00eb ul\u00ebt” ose inflamacion kronik.<\/span><\/p>\n Indi dhjamor \u00ebsht\u00eb treguar se luan nj\u00eb rol t\u00eb r\u00ebnd\u00ebsish\u00ebm n\u00eb inflamacionin e nivelit t\u00eb ul\u00ebt. Marr\u00ebdh\u00ebnia midis akumulimit t\u00eb tep\u00ebrt t\u00eb indit dhjamor dhe zhvillimit t\u00eb rezistenc\u00ebs ndaj insulin\u00ebs ose diabeti i tipit 2 \u00ebsht\u00eb i njohur p\u00ebr nj\u00eb koh\u00eb t\u00eb gjat\u00eb, por njohurit\u00eb p\u00ebr var\u00ebsit\u00eb reciproke jan\u00eb siguruar nga studimi i rasteve klinike t\u00eb lipodistrofis\u00eb, d.m.th. nj\u00eb gjendje n\u00eb t\u00eb cil\u00ebn lipodistrofia ( kongjenitale ose e fituar) ndodh, mosfunksionim i r\u00ebnd\u00ebsish\u00ebm i indit dhjamor ose mungon plot\u00ebsisht (lipoatrofi).<\/p>\n Njer\u00ebzit e prekur n\u00eb k\u00ebt\u00eb m\u00ebnyr\u00eb vuajn\u00eb nga rezistenca e r\u00ebnd\u00eb ndaj insulin\u00ebs me t\u00eb gjitha simptomat tipike, duke p\u00ebrfshir\u00eb diabetin e tipit 2, pra, k\u00ebto jan\u00eb \u00e7rregullime identike q\u00eb zakonisht gjenden n\u00eb gjendjen e lidhur me tepricat kronike t\u00eb l\u00ebnd\u00ebve ushqyese – obeziteti.<\/p>\n Ky paradoks i duksh\u00ebm mund t\u00eb shpjegohet me aft\u00ebsin\u00eb e indit dhjamor p\u00ebr t\u00eb p\u00ebrpunuar n\u00eb m\u00ebnyr\u00eb t\u00eb p\u00ebrshtatshme rrjedh\u00ebn e l\u00ebnd\u00ebve ushqyese, d.m.th., t\u00eb ruaj\u00eb lipidet n\u00eb rast t\u00eb furnizimit t\u00eb tyre t\u00eb shtuar (por jo t\u00eb p\u00ebrhersh\u00ebm) dhe t’i \u00e7liroj\u00eb ato n\u00eb procesin e lipoliz\u00ebs (dekompozimi i yndyrave t\u00eb grumbulluara n\u00eb yndyr\u00eb). qelizat).<\/p>\n N\u00eb rast t\u00eb munges\u00ebs s\u00eb plot\u00eb t\u00eb indit dhjamor (lipoatrofis\u00eb) ose kufizimit t\u00eb funksionit dhe sasis\u00eb s\u00eb tij (lipodistrofia), \u00ebsht\u00eb e qart\u00eb se trupi e ka humbur k\u00ebt\u00eb aft\u00ebsi “absorbuese” t\u00eb indit dhjamor dhe lipidet depozitohen n\u00eb inde t\u00eb tjera, ku ato. nd\u00ebrveprojn\u00eb ndjesh\u00ebm me metabolizmin e nd\u00ebrmjet\u00ebm dhe marrin pjes\u00eb n\u00eb zhvillimin e rezistenc\u00ebs ndaj insulin\u00ebs.<\/p>\n Tek njer\u00ebzit obez\u00eb, situata \u00ebsht\u00eb e ndryshme: energjia e tep\u00ebrt kronike \u00e7on n\u00eb nj\u00eb rritje graduale t\u00eb v\u00ebllimit t\u00eb qelizave yndyrore (adipocitet), dhe vet\u00ebm pasi t\u00eb arrihet nj\u00eb nivel i caktuar kritik i madh\u00ebsis\u00eb s\u00eb qelizave yndyrore, ndodh aktivizimi dhe p\u00ebrhapja e preadipociteve, dhe yndyra e re. krijohen qeliza.<\/p>\n \u00cbsht\u00eb v\u00ebrtetuar se sa m\u00eb e madhe t\u00eb jet\u00eb qeliza yndyrore, aq m\u00eb e madhe \u00ebsht\u00eb rezistenca ndaj insulin\u00ebs dhe rreziku i zhvillimit t\u00eb diabetit.<\/p>\n Inflamacioni kronik, i leht\u00eb karakterizohet nga rritja e prodhimit t\u00eb nj\u00eb numri citokinash (substanca t\u00eb ngjashme me proteinat q\u00eb p\u00ebrdoren p\u00ebr t\u00eb bashk\u00ebvepruar me qelizat dhe p\u00ebr t\u00eb transmetuar informacion) nga indi dhjamor, ve\u00e7an\u00ebrisht TNF-\u03b1, IL-6, IL-1, IL-8, nd\u00ebrsa zvog\u00eblohet prodhimi i citokinave, adiponektin\u00ebs antiinflamatore dhe leptin\u00ebs.<\/p>\n Makrofag\u00ebt q\u00eb jan\u00eb fiziologjikisht t\u00eb pranish\u00ebm n\u00eb indin dhjamor dhe q\u00eb rekrutohen n\u00eb nj\u00eb mas\u00eb m\u00eb t\u00eb madhe n\u00eb indin dhjamor gjat\u00eb zhvillimit t\u00eb obezitetit jan\u00eb p\u00ebrgjegj\u00ebs p\u00ebr prodhimin e k\u00ebtyre citokinave.<\/p>\n Makrofag\u00ebt n\u00eb indin dhjamor grumbullohen kryesisht rreth qelizave yndyrore t\u00eb m\u00ebdha, hipertrofike, q\u00eb vdesin ose t\u00eb vdekura.<\/p>\n Nj\u00eb fenomen i quajtur “stresi endoplazmatik i retikulumit” luan nj\u00eb rol t\u00eb r\u00ebnd\u00ebsish\u00ebm n\u00eb procesin e vdekjes qelizore t\u00eb qelizave yndyrore t\u00eb hipertrofuara. Kjo organel\u00eb nd\u00ebrqelizore kryen nj\u00eb funksion thelb\u00ebsor n\u00eb sintez\u00ebn e proteinave.<\/p>\n L\u00ebnd\u00ebt e tep\u00ebrta ushqyese jan\u00eb nj\u00eb nga faktor\u00ebt q\u00eb shkakton nj\u00eb k\u00ebrkes\u00eb t\u00eb shtuar p\u00ebr rrjetin endoplazmatik n\u00eb qelizat dhjamore. Nj\u00eb pjes\u00eb e p\u00ebrgjigjes ndaj k\u00ebtij stresi jan\u00eb ndryshimet e gjera n\u00eb metabolizmin e qelizave q\u00eb mund t\u00eb \u00e7ojn\u00eb n\u00eb vdekjen e qelizave.<\/p>\n N\u00eb nivelin e sot\u00ebm t\u00eb njohurive, shfaqja e rezistenc\u00ebs ndaj insulin\u00ebs p\u00ebr shkak t\u00eb gjendjes pro-inflamatore t\u00eb trupit mund t\u00eb p\u00ebrmblidhet me sekuenc\u00ebn e m\u00ebposhtme t\u00eb ngjarjeve: l\u00ebnd\u00ebt ushqyese t\u00eb tep\u00ebrta dhe aktiviteti fizik i pamjaftuesh\u00ebm \u00e7ojn\u00eb n\u00eb hipertrofi t\u00eb qelizave yndyrore dhe shqet\u00ebsime n\u00eb ndjeshm\u00ebrin\u00eb ndaj insulin\u00ebs. indet e synuara, ve\u00e7an\u00ebrisht muskujt.<\/p>\n Qelizat yndyrore hipertrofike, dhe p\u00ebr k\u00ebt\u00eb arsye indi dhjamor i ndryshuar, shkaktojn\u00eb m\u00eb tej nj\u00eb gjendje t\u00eb but\u00eb pro-inflamatore p\u00ebrmes prodhimit t\u00eb citokineve inflamatore dhe niveleve m\u00eb t\u00eb larta t\u00eb acideve yndyrore t\u00eb lira t\u00eb \u00e7liruara gjat\u00eb lipoliz\u00ebs n\u00eb qelizat dhjamore.<\/p>\n Nd\u00ebrsa s\u00ebmundja p\u00ebrparon, makrofag\u00ebt n\u00eb indin dhjamor rriten dhe makrofag\u00ebt thirren n\u00eb indin dhjamor p\u00ebr t\u00eb eliminuar qelizat dhjamore q\u00eb vdesin.<\/p>\n K\u00ebta makrofag\u00eb prodhojn\u00eb substanca pro-inflamatore me intensitet t\u00eb ul\u00ebt dhe \u00e7ojn\u00eb n\u00eb rezistenc\u00eb ndaj insulin\u00ebs. Kjo krijon t\u00eb dy kushtet baz\u00eb p\u00ebr zhvillimin e diabetit t\u00eb tipit 2.<\/p>\n P\u00ebr shkak se inflamacioni i but\u00eb kronik \u00ebsht\u00eb nj\u00eb aspekt i obezitetit abdominal, ka t\u00eb ngjar\u00eb q\u00eb ekspozimi i vazhduesh\u00ebm ndaj citokinave inflamatore nga makrofag\u00ebt t\u00eb \u00e7oj\u00eb n\u00eb zhvillimin e ateroskleroz\u00ebs.<\/p>\n Pacient\u00ebt obez\u00eb kishin nivele m\u00eb t\u00eb larta t\u00eb amiloidit qarkullues (nj\u00eb pjes\u00eb e protein\u00ebs q\u00eb nd\u00ebrtohet n\u00eb hap\u00ebsir\u00ebn nd\u00ebrqelizore gjat\u00eb gjendjeve t\u00eb s\u00ebmundjes).<\/p>\n Prandaj, disa autor\u00eb e vendosin obezitetin, diabetin dhe s\u00ebmundjen e Alzheimerit t\u00eb pakt\u00ebn n\u00eb m\u00ebnyr\u00eb indirekte. S\u00ebmundjet q\u00eb lidhen me k\u00ebt\u00eb lloj inflamacioni p\u00ebrfshijn\u00eb ateroskleroz\u00ebn, diabetin, tromboz\u00ebn, infarktin e miokardit, goditjen n\u00eb tru, \u00e7rregullimet metabolike dhe demenc\u00ebn.<\/p>\n Morinda citrifolia (quhet noni n\u00eb gjuh\u00ebt polineziane) \u00ebsht\u00eb nj\u00eb frut unik ekzotik q\u00eb p\u00ebrmban nj\u00eb s\u00ebr\u00eb substancash t\u00eb r\u00ebnd\u00ebsishme, aminoacide, vitamina dhe minerale. Fruti Noni redukton proceset inflamatore n\u00eb trup dhe mb\u00ebshtet aktivitetin e sh\u00ebndetsh\u00ebm t\u00eb qelizave dhe proliferimin e qelizave. Calivita<\/a> Organic Noni<\/a> p\u00ebrmir\u00ebsohet m\u00eb tej nga efekti i trefisht\u00eb i sheg\u00ebs organike, qershive organike dhe rrushit organik t\u00eb shtuar n\u00eb Noni organik, gj\u00eb q\u00eb i jep produktit nj\u00eb arom\u00eb intensive frutash. Produkti Organic Noni vjen nga bujq\u00ebsia organike e certifikuar.<\/p>\n Burimi: <\/span>https:\/\/czech.calivita.com\/organic-noni-a-zanet-s-nizkou-aktivitou<\/span><\/p>\n<\/div>\n (etiketaP\u00ebrkthe) organike jo<\/p>\n","protected":false},"excerpt":{"rendered":" Inflamacioni ose reaksioni inflamator \u00ebsht\u00eb nj\u00eb aft\u00ebsi stereotipike, komplekse, e fituar nga zhvillimi i organizmave t\u00eb gjall\u00eb p\u00ebr t’iu p\u00ebrgjigjur…<\/p>\n","protected":false},"author":1,"featured_media":12412,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[609,607,606,605,608],"class_list":["post-12411","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-calivita","tag-ateroskleroze","tag-diabet","tag-inflamacion","tag-organike","tag-rezistence-ndaj-insulines"],"_links":{"self":[{"href":"https:\/\/vitashop.info\/ks\/wp-json\/wp\/v2\/posts\/12411","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vitashop.info\/ks\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vitashop.info\/ks\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vitashop.info\/ks\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vitashop.info\/ks\/wp-json\/wp\/v2\/comments?post=12411"}],"version-history":[{"count":0,"href":"https:\/\/vitashop.info\/ks\/wp-json\/wp\/v2\/posts\/12411\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vitashop.info\/ks\/wp-json\/wp\/v2\/media\/12412"}],"wp:attachment":[{"href":"https:\/\/vitashop.info\/ks\/wp-json\/wp\/v2\/media?parent=12411"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vitashop.info\/ks\/wp-json\/wp\/v2\/categories?post=12411"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vitashop.info\/ks\/wp-json\/wp\/v2\/tags?post=12411"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Roli i indit dhjamor n\u00eb inflamacion<\/h2>\n
Nj\u00eb paradoks i duksh\u00ebm – inflamacioni dhe rezistenca ndaj insulin\u00ebs<\/h2>\n
Cila \u00ebsht\u00eb lidhja midis obezitetit dhe rezistenc\u00ebs ndaj insulin\u00ebs dhe diabetit?<\/h2>\n
Prodhimi i citokin\u00ebs n\u00eb inflamacion t\u00eb leht\u00eb<\/h3>\n
Ndryshimet n\u00eb metabolizmin qelizor<\/h3>\n
Shfaqja e rezistenc\u00ebs ndaj insulin\u00ebs, cilat jan\u00eb shkaqet e saj?<\/h3>\n
Ateroskleroza, cilat jan\u00eb shkaqet e saj dhe lidhja e saj me inflamacionin?<\/h2>\n
Organic Noni \u00ebsht\u00eb nj\u00eb noni e re organike me fruta organike<\/h2>\n