\n
<\/p>\n
Selen je nezbytn\u00fdm prvkem pro spr\u00e1vn\u00e9 fungov\u00e1n\u00ed na\u0161eho t\u011bla a jeho nedostatek m\u016f\u017ee p\u0159edstavovat velk\u00fd probl\u00e9m postihuj\u00edc\u00ed zejm\u00e9na region, kde \u017eijeme. Na jedn\u00e9 stran\u011b na\u0161e z\u00e1kladn\u00ed potraviny obsahuj\u00ed mal\u00e9 mno\u017estv\u00ed tohoto z\u00e1kladn\u00edho prvku, proto\u017ee zem\u011b obsahuje mal\u00e9 mno\u017estv\u00ed selenu; na druhou stranu nej\u00edme potraviny s vysok\u00fdm obsahem selenu (ryby, mu\u0161le, srdce nebo j\u00e1tra). V n\u011bkter\u00fdch zem\u00edch se vst\u0159eb\u00e1v\u00e1n\u00ed selenu za posledn\u00edch 20\u201330 let sn\u00ed\u017eilo o 50 %, i kdy\u017e tento prvek m\u016f\u017ee hr\u00e1t d\u016fle\u017eitou roli v prevenci n\u011bkter\u00fdch onemocn\u011bn\u00ed.<\/span><\/p>\n Selen je nezbytn\u00fd pro \u0161t\u00edtnou \u017el\u00e1zu, jej\u00ed spr\u00e1vn\u00e9 fungov\u00e1n\u00ed a tvorbu hormon\u016f. N\u011bkter\u00e9 studie nav\u00edc uk\u00e1zaly, \u017ee selen m\u016f\u017ee pomoci p\u0159i l\u00e9\u010db\u011b onemocn\u011bn\u00ed \u0161t\u00edtn\u00e9 \u017el\u00e1zy. V p\u0159\u00edpad\u011b autoimunitn\u00ed tyreoiditidy m\u016f\u017ee selen sn\u00ed\u017eit z\u00e1n\u011bt, zlep\u0161it kvalitu \u017eivota a b\u00fdt u\u017eite\u010dn\u00fd p\u0159i l\u00e9\u010db\u011b nebo prevenci hypotyre\u00f3zy, ke kter\u00e9 doch\u00e1z\u00ed b\u011bhem t\u011bhotenstv\u00ed nebo po n\u011bm.<\/span><\/p>\n Podle v\u00fdsledk\u016f italsk\u00e9 studie mohou n\u00edzk\u00e9 hladiny selenu sn\u00ed\u017eit \u0161ance na ot\u011bhotn\u011bn\u00ed, proto\u017ee pohyblivost a \u00fa\u010dinnost mu\u017esk\u00fdch spermi\u00ed s n\u00edzkou hladinou selenu byla v\u00fdrazn\u011b ni\u017e\u0161\u00ed, stejn\u00e1 studie tak\u00e9 prok\u00e1zala souvislost mezi n\u00edzkou hladinou selenu a rizikem potratu. u \u017een. Podle britsk\u00e9ho v\u00fdzkumu m\u016f\u017ee nedostatek selenu zv\u00fd\u0161it riziko toxick\u00e9 otravy krve b\u011bhem t\u011bhotenstv\u00ed.<\/span><\/p>\n Na z\u00e1klad\u011b p\u0159edchoz\u00edch zku\u0161enost\u00ed nedostatek selenu, kter\u00fd se v\u00fdrazn\u011b odchyluje od optim\u00e1ln\u00edch hodnot, zp\u016fsobuje rakovinu jater, jater a \u017elu\u010dn\u00edku a nov\u00e9 v\u00fdzkumy nazna\u010duj\u00ed, \u017ee suplementace selenem m\u00e1 pozitivn\u00ed vliv na ran\u00e1 st\u00e1dia rakoviny.<\/span><\/p>\n Studie zahrnovala \u017eeny s cervik\u00e1ln\u00ed intraepiteli\u00e1ln\u00ed neoplazi\u00ed (jej\u00ed b\u011b\u017en\u00e1 zkratka je CIN); \u017eeny u\u017e\u00edvaly placebo nebo 200 \u03bcg selenu po dobu \u0161esti m\u011bs\u00edc\u016f. Zlep\u0161en\u00ed bylo po \u0161esti m\u011bs\u00edc\u00edch pozorov\u00e1no u 88 % pacient\u016f l\u00e9\u010den\u00fdch selenem a pouze u 56 % ve skupin\u011b s placebem. Ve skupin\u011b u\u017e\u00edvaj\u00edc\u00ed selen byly nav\u00edc zaznamen\u00e1ny dal\u0161\u00ed pozitivn\u00ed zm\u011bny: normalizovala se hladina krevn\u00edho cukru a zv\u00fd\u0161ila se citlivost na inzul\u00edn a hladina dobr\u00e9ho HDL cholesterolu.<\/span><\/p>\n Proteiny obsahuj\u00edc\u00ed selen hraj\u00ed antioxida\u010dn\u00ed roli zvl\u00e1\u0161t\u011b d\u016fle\u017eitou nejen ve \u0161t\u00edtn\u00e9 \u017el\u00e1ze, ale tak\u00e9 v srdci. Podle anal\u00fdzy, kter\u00e1 shrnula v\u00fdsledky 25 studi\u00ed, spolu hladiny selenu a riziko ischemick\u00e9 choroby srde\u010dn\u00ed \u00fazce souvis\u00ed: v p\u0159\u00edpadech, kdy je p\u0159\u00edjem selenu vysok\u00fd, je riziko srde\u010dn\u00edch probl\u00e9m\u016f n\u00edzk\u00e9!<\/span><\/p>\n Zdroje:<\/span><\/p>\n Preddiagnostick\u00fd stav selenu a riziko hepatobili\u00e1rn\u00edho karcinomu ve skupin\u011b European Prospective Investigation into Cancer and Nutrition \u2013 Hughes DJ., Am J Clin Nutr. 29. \u010dervna 2016.<\/span><\/p>\n Relativn\u011b vysok\u00e9 riziko \u00famrtnosti u star\u0161\u00edch \u0161v\u00e9dsk\u00fdch subjekt\u016f s n\u00edzkou hladinou selenu \u2013 Alehagen et al., European Journal of Clinical Nutrition (2016) 70, 91\u201396<\/span><\/p>\n Stav selenu a kardiovaskul\u00e1rn\u00ed onemocn\u011bn\u00ed: metaanal\u00fdza prospektivn\u00edch observa\u010dn\u00edch studi\u00ed a randomizovan\u00fdch kontrolovan\u00fdch studi\u00ed \u2013 Zhang et al., European Journal of Clinical Nutrition 70, 162-169 (\u00fanor 2016)<\/span><\/p>\n Stav n\u00edzk\u00e9 populace selenu je spojen se zv\u00fd\u0161enou prevalenc\u00ed onemocn\u011bn\u00ed \u0161t\u00edtn\u00e9 \u017el\u00e1zy \u2013 Wu a kol., J Clin Endocrinol Metab. listopad 2015;100(11):4037-47.<\/span><\/p>\n Asociace mezi funkc\u00ed selenu a srde\u010dn\u00edm onemocn\u011bn\u00edm – Hiraoka Y. Nihon Rinsho. \u010dervenec 2016;74(7):1192-8.<\/span><\/p>\n Selen a \u0161t\u00edtn\u00e1 \u017el\u00e1za – Josef K\u00f6hrleCurr Opin Endokrinol Diabetes Obes. \u0159\u00edjen 2015;22(5):392-401.<\/span><\/p>\n A szel\u00e9n szerepeaz endocrin betegs\u00e9gekben \u2013 Bal\u00e1zs Cs., R\u00e1cz K., Orv Hetil. 13. \u0159\u00edjna 2013;154(41):1628-35.<\/span><\/p>\n Vliv suplementace selenu na poporodn\u00ed stav \u0161t\u00edtn\u00e9 \u017el\u00e1zy u t\u011bhotn\u00fdch \u017een s autoprotil\u00e1tkami tyreoid\u00e1ln\u00ed peroxid\u00e1zy – Negro R et al. (2007) J Clin Endocrinol Metab 92:1263\u20131268<\/span><\/p>\n N\u00edzk\u00fd stav selenu v populaci je spojen se zv\u00fd\u0161enou prevalenc\u00ed onemocn\u011bn\u00ed \u0161t\u00edtn\u00e9 \u017el\u00e1zy – Qian Wu et al., J Clin Endocrinol Metab<\/span><\/p>\n Selen a lidsk\u00e9 zdrav\u00ed \u2013 Rayman Lancet 2012; 379: 1256\u201368<\/span><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":" Pro hormony \u0161t\u00edtn\u00e9 \u017el\u00e1zy Selen je nezbytn\u00fdm prvkem pro spr\u00e1vn\u00e9 fungov\u00e1n\u00ed na\u0161eho t\u011bla a jeho nedostatek m\u016f\u017ee p\u0159edstavovat velk\u00fd probl\u00e9m…<\/p>\n","protected":false},"author":1,"featured_media":7188,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-10261","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-calivita"],"_links":{"self":[{"href":"https:\/\/vitashop.info\/cz\/wp-json\/wp\/v2\/posts\/10261","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vitashop.info\/cz\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vitashop.info\/cz\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vitashop.info\/cz\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vitashop.info\/cz\/wp-json\/wp\/v2\/comments?post=10261"}],"version-history":[{"count":0,"href":"https:\/\/vitashop.info\/cz\/wp-json\/wp\/v2\/posts\/10261\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vitashop.info\/cz\/wp-json\/wp\/v2\/media\/7188"}],"wp:attachment":[{"href":"https:\/\/vitashop.info\/cz\/wp-json\/wp\/v2\/media?parent=10261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vitashop.info\/cz\/wp-json\/wp\/v2\/categories?post=10261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vitashop.info\/cz\/wp-json\/wp\/v2\/tags?post=10261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}\u0160t\u00edtn\u00e1 \u017el\u00e1za<\/h3>\n
T\u011bhotenstv\u00ed<\/h3>\n
Rakovina<\/h3>\n
Selen a srdce<\/h3>\n